OBO Travel lists 85 hotels in La Mesa, United States, 85 of them with photo galleries and full descriptions. The mix includes 4 five-star and 27 four-star properties, alongside mid-range and budget stays. Well-rated picks include La Valencia, Omni San Diego Hotel, Pendry San Diego and The Westin San Diego Bayview. Prices come live from our suppliers when you pick your dates, with the cancellation policy shown before you book.
Top hotels in La Mesa
Verified availability first, then star rating and photo quality.
La Valencia
LA JOLLA
Enjoy a range of recreational amenities at this hotel, including an outdoor pool, spa tub, and fitness center. Additi...
Omni San Diego Hotel
SAN DIEGO
Just steps away, you will discover the heart of downtown San Diego. Our hotel near Petco Park and the Gaslamp Quarter...
Pendry San Diego
SAN DIEGO
Relax at the full-service spa, where you can enjoy massages, body treatments, and facials. If you're looking for recr...
The Westin San Diego Bayview
San Diego
Relax and unwind with massages and facials. You're sure to appreciate the recreational amenities, including an outdoo...
Paradise Point
SAN DIEGO
When you stay at Paradise Point Resort & Spa in San Diego, you'll be on the beach, within a 5-minute drive of Mission...
Alma San Diego Downtown, a Tribute Portfolio Hotel
SAN DIEGO
Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. Additional amenities...
Andaz San Diego, by Hyatt
SAN DIEGO
Located in the energetic Gaslamp Quarter, Andaz San Diego offers modern boutique accommodations, personalized service...
Best Western Plus Island Palms Hotel & Marina
SAN DIEGO
With a waterfront location close to Ocean Beach, SeaWorld®, and the San Diego Zoo®, the Best Western Plus Island Palm...
Courtyard San Diego Sorrento Valley
SAN DIEGO
Enjoy numerous amenities, including an outdoor pool, spa tub, and fitness center. This hotel also offers complimentar...
Hilton San Diego Bayfront
San Diego
Pamper yourself with a visit to the spa, which offers massages, body treatments, and facials. You're sure to apprecia...
Hilton San Diego Gaslamp Quarter
SAN DIEGO
Situated at the entrance to the historic Gaslamp Quarter, the Hilton San Diego Gaslamp Quarter offers convenient acce...
Horton Grand Hotel
SAN DIEGO
The Horton Grand, a Victorian hotel in San Diego's Downtown/Gaslamp Quarter, offers 132 individually decorated guestr...
Hotel Republic
SAN DIEGO
Take advantage of recreation opportunities such as a fitness center or take in the view from a rooftop terrace and a...
Hyatt Regency La Jolla at Aventine
SAN DIEGO
Set on 4. 5 hectares, the luxurious Hyatt Regency La Jolla hotel enjoys a convenient location in La Jolla, a seaside...
Hyatt Regency Mission Bay Spa and Marina
SAN DIEGO
Overlooking the Pacific Ocean, Mission Bay and the marina, this luxury hotel is excellently set on 3. 2 hectares in M...
Manchester Grand Hyatt San Diego
SAN DIEGO
Boasting amazing views over San Diego harbour from its frontline position, the splendid luxury hotel Manchester Grand...
Marriott Marquis San Diego Marina
San Diego
Relax at the full-service spa, where you can enjoy massages, body treatments, and facials. You're sure to appreciate...
Marriott San Diego Mission Valley
San Diego
Take advantage of recreation opportunities including an outdoor pool and a fitness center. Additional amenities at th...
San Diego Marriott Gaslamp Quarter
SAN DIEGO
Enjoy a stay at this hotel, featuring a nightclub, a 24-hour fitness center, concierge services, gift shops, and even...
San Diego Mission Bay Resort
SAN DIEGO
Situated directly on Mission Bay in the heart of San Diego, this Noble House resort (formerly the Hilton San Diego Re...
Sheraton San Diego Resort
SAN DIEGO
Sheraton San Diego Resort dazzles guests with spectacular views of the marina or downtown skyline. Experience San Die...
SpringHill Suites San Diego Downtown/Bayfront
San Diego
Enjoy recreational amenities such as an outdoor pool and a fitness center. Additional amenities at this hotel include...
SpringHill Suites San Diego Mission Valley
San Diego
Enjoy amenities including an outdoor pool and fitness center. This hotel also offers complimentary Wi-Fi, concierge s...
The Dextro, BW Premier Collection
SAN DIEGO
Located in the heart of San Diego's Little Italy, The Dextro, BW Premier Collection is a short drive from the USS Mid...
Luxury hotels in La Mesa
Five-star properties with photo galleries.
La Valencia
LA JOLLA
Enjoy a range of recreational amenities at this hotel, including an outdoor pool, spa tub, and fitness center. Additi...
Omni San Diego Hotel
SAN DIEGO
Just steps away, you will discover the heart of downtown San Diego. Our hotel near Petco Park and the Gaslamp Quarter...
Pendry San Diego
SAN DIEGO
Relax at the full-service spa, where you can enjoy massages, body treatments, and facials. If you're looking for recr...
The Westin San Diego Bayview
San Diego
Relax and unwind with massages and facials. You're sure to appreciate the recreational amenities, including an outdoo...
Best value hotels in La Mesa
Three and four-star stays with photos and descriptions.
The Westgate
SAN DIEGO
Welcome to your home away from home, a uniquely palatial sanctuary on the edge of San Diego's Gaslamp district. Desig...
The Westin San Diego Gaslamp Quarter
SAN DIEGO
Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. This hotel also featu...
Tower 23
San Diego
Enjoy stunning rooftop terrace views at this 44-room hotel in Pacific Beach. Stay connected with complimentary Wi-Fi...
Hard Rock Hotel San Diego
SAN DIEGO
The Hard Rock Hotel San Diego sits at the entrance to the historic Gaslamp Quarter, San Diego's vibrant dining and en...
The Dana on Mission Bay
SAN DIEGO
Dip into one of the 2 outdoor swimming pools or 2 spa tubs and enjoy other recreational amenities, which include a fi...
Pacific Terrace
SAN DIEGO
Enjoy amenities including an outdoor pool, a spa tub, and a 24-hour fitness center. This hotel also offers compliment...
Indigo San Diego-Gaslamp Quarter
SAN DIEGO
The Hotel Indigo® San Diego Gaslamp Quarter hotel is at one with the neighborhood. Join us for great MLB action as th...
Catamaran Resort
SAN DIEGO
Relax at the full-service spa, where you can enjoy massages and facials. You can take advantage of recreational ameni...
Popular hotel chains in La Mesa
Every property of a chain on one page, whichever supplier offers it.
Frequently asked questions about hotels in La Mesa
How many hotels are there in La Mesa?
OBO Travel lists 85 hotels in La Mesa, United States, including 4 five-star and 27 four-star properties.
What are the best hotels in La Mesa?
Popular choices with strong ratings and photo galleries include La Valencia, Omni San Diego Hotel, Pendry San Diego and The Westin San Diego Bayview. Open any hotel to see rooms, facilities and live prices for your dates.
When is the best time to visit La Mesa?
Hotel prices in La Mesa vary by season and local events. Enter your dates to compare live rates, and check a few alternatives if you are flexible.
How much does a hotel in La Mesa cost?
Rates depend on dates, room type and board basis. Pick your dates on any hotel page to see live prices from our suppliers.
Nearby destinations
Other places to stay within easy reach of La Mesa.